《中国神经再生研究（英文版）》最新发布

2023年第5期目次

Neural Regeneration Research

Volume 18 / Number 5

综述

Vimentin as a potential target for diverse nervous system diseases

波形蛋白作为多种神经系统疾病的潜在干预靶点

Kang-Zhen Chen, Shu-Xian Liu, Yan-Wei Li, Tao He, Jie Zhao, Tao Wang, Xian-Xiu Qiu, Hong-Fu Wu

The critical role of the endolysosomal system in cerebral ischemia

内溶酶体系统在脑缺血中的关键作用

Hui-Yi Zhang, Ye Tian, Han-Yan Shi, Ya Cai, Ying Xu

Chx10+V2a interneurons in spinal motor regulation and spinal cord injury

Chx10+V2a中间神经元在运动调节和脊髓损伤治疗中的作用

Wen-Yuan Li, Ling-Xiao Deng, Feng-Guo Zhai, Xiao-Yu Wang, Zhi-Gang Li, Ying Wang

Clemastine in remyelination and protection of neurons and skeletal muscle after spinal cord injury

展开全文

氯马斯汀在脊髓损伤后髓鞘再生及神经元和骨骼肌保护中的作用

Ali Myatich, Azizul Haque, Christopher Sole, Naren L. Banik

Patient-specific monocyte-derived microglia as a screening tool for neurodegenerative diseases

患者特异性单核细胞衍生的小胶质细胞作为神经退行性疾病的筛查工具

Hazel Quek, Anthony R. White

The effects and potential of microglial polarization and crosstalk with other cells of the central nervous system in the treatment of Alzheimer’s disease

小胶质细胞极化和与其deepbit他中枢神经系统细胞交叉对话可能成为治疗阿尔茨海默病的潜力

Yi-Ge Wu, Li-Juan Song, Li-Jun Yin, Jun-Jun Yin, Qing Wang, Jie-Zhong Yu, Bao-Guo Xiao, Cun-Gen Ma

Novel therapeutic strategies targeting mitochondria as a gateway in neurodegeneration

靶向线粒体作为神经退行性变通路的新治疗策略

Diogo Trigo, José João Vitória, Odete A. B. da Cruz e Silva

Molecular hallmarks of long non-coding RNAs in aging and its significant effect on aging-associated diseases

长链非编码RNA在衰老过程中的分子标志及其对衰老相关疾病的显著影响

Syed Aoun Mehmood Sherazi, Asim Abbasi, Abdullah Jamil, Mohammad Uzair, Ayesha Ikram, Shanzay Qamar, Adediji Ayomide Olamide, Muhammad Arshad, Peter J. Fried, Milos Ljubisavljevic, Ran Wang, Shahid Bashir

Anti-IgLON5 disease: a novel topic beyond neuroimmunology

抗IgLON5疾病：超越神经免疫学的新课题

Yi-ZongHeng Zhang, You Ni, Yi-Ning Gao, Ding-Ding Shen, Lu He, Dou Yin, Huan-Yu Meng, Qin-Ming Zhou, Ji Hu, Sheng Chen

Targeting the nitric oxide/cGMP signaling pathway to treat chronic pain

靶向一氧化氮/cGMP信号通路治疗慢性疼痛

Dan-Yang Li, Shao-Jie Gao, Jia Sun, Long-Qing Zhang, Jia-Yi Wu, Fan-He Song, Dai-Qiang Liu, Ya-Qun Zhou, Wei Mei

Neurosteroids as stress modulators and neurotherapeutics: lessons from the retina

神经类固醇作为压力调节剂和神经治疗剂：视网膜的教训

Yukitoshi Izumi, Makoto Ishikawa, Toru Nakazawa, Hiroshi Kunikata, Kota Sato, Douglas F. Covey, Charles F. Zorumski

Myelinosome organelles in pathological retinas: ubiquitous presence and dual role in ocular proteostasis maintenance

病理视网膜中的髓鞘细胞器：普遍存在和在眼部蛋白质稳态维持中的双重作用

Marina G. Yefimova

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

糖尿病视网膜病变中的炎症：在发病机制中的可能作用和对治疗的潜在影响

Lei Tang, Guo-Tong Xu, Jing-Fa Zhang

观点

Neuroinflammation and glial activation in the central nervous system: a metabolic perspective

中枢神经系统的神经炎症和神经胶质激活：代谢视角

Assunta Virtuoso, Ciro De Luca, Sohaib Ali Korai, Michele Papa, Giovanni Cirillo

Endocannabinoid control of neuroinflammation in traumatic brain injury by monoacylglycerol lipase in astrocytes

星形胶质细胞中单酰基甘油脂肪酶对创伤性脑损伤神经炎症的内源性大麻素控制

Chu Chen

Olfactory dysfunction as a common biomarker for neurodegenerative and neuropsychiatric disorders

嗅觉功能障碍作为神经退行性和神经精神疾病的常见生物标志物

David Slabik, Olga Garaschuk

LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities

LL-37 和 CsgC 体现deepbit了抗淀粉样蛋白、抗微生物和抗生物膜蛋白活性之间的串扰

Jaime Santos, Salvador Ventura, Irantzu Pallarès

评论

Mechanotransduction mechanisms in CNS glia

中枢神经胶质细胞的机械转导机制

Brenan Cullimore, Jackson Baumann, Christopher N. Rudzitis, Andrew O. Jo, Denisa Kirdajova, David Križaj

研究原著

脑损伤与神经再生

Blocking postsynaptic density-93 binding to C‑X3‑C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke

阻断PSD-93-CX3CL1的相互作用促进急性缺血性脑卒中后小胶质细胞的表型转化

Xiao-Wei Cao, Hui Yang, Xiao-Mei Liu, Shi-Ying Lou, Li-Ping Kong, Liang-Qun Rong, Jun-Jun Shan, Yun Xu, Qing-Xiu Zhang

Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion

琥珀酸积累诱导Cdc42琥珀酰化抑制脑缺血再灌注后神经干细胞的增殖

Lin-Yan Huang, Ju-Yun Ma, Jin-Xiu Song, Jing-Jing Xu, Rui Hong, Hai-Di Fan, Heng Cai, Wan Wang, Yan-Ling Wang, Zhao-Li Hu, Jian-Gang Shen, Su-Hua Qi

Neutrophil-derived interleukin-17A participates in neuroinflammation induced by traumatic brain injury

浸润中性粒细胞的白细胞介素17A参与创伤性脑损伤诱发的神经炎症

Xiao-Jian Xu, Qian-Qian Ge, Meng-Shi Yang, Yuan Zhuang, Bin Zhang, Jin-Qian Dong, Fei Niu, Hao Li, Bai-Yun Liu

Integrin binding peptides facilitate growth and interconnected vascularlike network formation of rat primary cortical vascular endothelial cells in vitro

整合素结合肽促进大鼠原代大脑皮质血管内皮细胞的生长和血管样网络形成

Ram Kuwar, Xuejun Wen, Ning Zhang, Dong Sun

A benchtop brain injury model using resected donor tissue from patients with Chiari malformation

小脑扁桃体下疝畸形患者切除的供体组织建立的脑损伤模型

Jacqueline A. Tickle, Jon Sen, Christopher Adams, David N. Furness, Rupert Price, Viswapathi Kandula, Nikolaos Tzerakis, Divya M. Chari

脊髓损伤与神经再生

Double-target neural circuit-magnetic stimulation improves motor function in spinal cord injury by attenuating astrocyte activation

双靶区神经环路磁刺激减弱脊髓损伤后星形胶质细胞活化以改善运动功能

Dan Zhao, Ye Zhang, Ya Zheng, Xu-Tong Li, Cheng-Cheng Sun, Qi Yang, Qing Xie, Dong-Sheng Xu

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway

骨髓间充质干细胞和运动通过激活PI3K/AKT/mTOR通路恢复脊髓损伤后的运动功能

Xin Sun, Li-Yi Huang, Hong-Xia Pan, Li-Juan Li, Lu Wang, Gai-Qin Pei, Yang Wang, Qing Zhang, Hong-Xin Cheng, Cheng-Qi He, Quan Wei

Alterations in gut microbiota are related to metabolite profiles in spinal cord injury

脊髓损伤后肠道菌群变化与代谢物谱相关

Jian-Ning Kang, Zheng-Fang Sun, Xin-Yu Li, Xiao-Di Zhang, Zheng-Xin Jin, Ce Zhang, Ying Zhang, Hui-Yun Wang, Na-Na Huang, Jian-Hao Jiang, Bin Ning

Assessment of hindlimb motor recovery after severe thoracic spinal cord injury in rats: classification of CatWalk XT® gait analysis parameters

严重胸段脊髓损伤大鼠的后肢运动功能恢复：CatWalk XT®步态分析

Guoli Zheng, Hao Zhang, Mohamed Tail, Hao Wang, Johannes Walter, Thomas Skutella, Andreas Unterberg, Klaus Zweckberger, Alexander Younsi

神经退行性疾病与神经再生

Neural progenitor cells derived from fibroblasts induced by small molecule compounds under hypoxia for treatment of Parkinson’s disease in rats

小分子化合物可在低氧环境下诱导成纤维细胞重编程为神经祖细胞治疗帕金森病

Yu Guo, Yuan-Yuan Wang, Ting-Ting Sun, Jia-Jia Xu, Pan Yang, Cai-Yun Ma, Wei-Jun Guan, Chun-Jing Wang, Gao-Feng Liu, Chang-Qing Liu

Neuroprotective effects of insulin-like growth factor-2 in 6-hydroxydopamineinduced cellular and mouse models of Parkinson’s disease

胰岛素样生长因子 2 对6-羟多巴胺诱导帕金森病小鼠模型的神经保护作用

Hai-Ying Zhang, Yong-Cheng Jiang, Jun-Rui Li, Jia-Nan Yan, Xin-Jue Wang, Jia-Bing Shen, Kai-Fu Ke, Xiao-Su Gu

Impact of cognition-related single nucleotide polymorphisms on brain imaging phenotype in Parkinson’s disease

认知相关单核苷酸多态性对帕金森病患者脑表型的影响

Ting Shen, Jia-Li Pu, Ya-Si Jiang, Yu-Mei Yue, Ting-Ting He, Bo-Yi Qu, Shuai Zhao, Ya-Ping Yan, Hsin-Yi Lai, Bao-Rong Zhang

Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson’s disease

前额叶皮质中胶质细胞系源性神经营养因子减少可引起帕金森病认知障碍

Chuan-Xi Tang, Jing Chen, Kai-Quan Shao, Ye-Hao Liu, Xiao-Yu Zhou, Cheng-Cheng Ma, Meng-Ting Liu, Ming-Yu Shi, Piniel Alphayo Kambey, Wei Wang, Abiola Abdulrahman Ayanlaja, Yi-Fang Liu, Wei Xu, Gang Chen, Jiao Wu, Xue Li, Dian-Shuai Gao

周围神经损伤与神经再生

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects

加载活化许旺细胞的人发角蛋白骨架构建新型人工神经移植物可桥接修复周围神经缺损

Han-Jun Qin, Hang Li, Jun-Ze Chen, Kai-Rui Zhang, Xing-Qi Zhao, Jian-Qiang Qin, Bin Yu, Jun Yang

Long noncoding RNA Pvt1 promotes the proliferation and migration of Schwann cells by sponging microRNA-214 and targeting c-Jun following peripheral nerve injury

长链非编码RNA Pvt1促进损伤周围神经许旺细胞增殖与迁移：海绵化靶向cJun的miRNA-214

Bin Pan, Di Guo, Li Jing, Ke Li, Xin Li, Gen Li, Xiao Gao, Zhi-Wen Li, Wei Zhao, Hu Feng, Meng-Han Cao

视神经损伤与神经再生

Overexpressing NeuroD1 reprograms Müller cells into various types of retinal neurons

过表达NeuroD1可将Müller细胞重新编程为多种类型的视网膜神经元

Di Xu, Li-Ting Zhong, Hai-Yang Cheng, Zeng-Qiang Wang, Xiong-Min Chen, Ai-Ying Feng, Wei-Yi Chen, Gong Chen, Ying Xu

Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization

piR-1245是视网膜新生血管形成的治疗靶点

Yong Yu, Li-Kun Xia, Yu Di, Qing-Zhu Nie, Xiao-Long Chen

Ocular manifestations of central insulin resistance

中枢胰岛素抵抗的眼部表现

Muneeb A. Faiq, Trina Sengupta, Madhu Nath, Thirumurthy Velpandian, Daman Saluja, Rima Dada, Tanuj Dada, Kevin C. Chan